At what temperature must the autoclave be set in order to sterilize general surgical packs and wrapped items?

The correct temperature for sterilizing general surgical packs and wrapped items in an autoclave is 250°F (121°C). This temperature is commonly used in veterinary and medical settings for effective sterilization because it facilitates the destruction of most bacteria, viruses, and spores in a reasonable time frame. The use of steam under pressure at this temperature allows for effective penetration through surgical packs and wrappings, ensuring that all surfaces are adequately sterilized.

Using this temperature for autoclaving provides a balance between effective microbial kill and maintaining the integrity of the items being sterilized. This is crucial in a surgical environment where any residual microorganisms could pose significant risks to patient safety.

Other temperature choices listed are either lower than needed for effective sterilization or higher than necessary, which may damage certain instruments or materials.